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Pathways Recommended:	Vitamin D Related/Nuclear Receptor

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Vitamin A acetate-d<sub>4</sub>

" in MedChemExpress (MCE) Product Catalog:

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9916

Inhibitors & Agonists

Screening Libraries

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179

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MCE Kits

Inhibitory Antibodies

980

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2983

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2694

Isotope-Labeled Compounds

614

Antibodies

Click Chemistry

Targets Recommended: VD/VDR P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0143S2

Niacin-d4 Nicotinic acid-d<sub>4sub>; Vitamin B3-d<sub>4sub>	Autophagy Endogenous Metabolite	Metabolic Disease
Niacin-d₄ is the deuterium labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

HY-N0679S4

Retinyl acetate-d4 Retinol acetate-d<sub>4sub>; Vitamin A acetate-d<sub>4sub>	Isotope-Labeled Compounds	Cancer
Retinyl acetate-d₄ is the deuterium labeled Retinyl acetate[1]. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities[2].

HY-16637S1

Folic acid-d4 Vitamin B9-d<sub>4sub>; Vitamin M-d<sub>4sub>	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
Folic acid-d₄ is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-N0684S1

Vitamin K1-d4 Phylloquinone-d<sub>4sub>; Phytomenadione-d<sub>4sub>	Endogenous Metabolite	Cardiovascular Disease
Vitamin K1-d₄ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1].

HY-B0579S2

Cyclosporin A acetate-d4 Cyclosporine A acetate-d<sub>4sub>; Ciclosporin A acetate-d<sub>4sub>; CsA acetate-d<sub>4sub>	Isotope-Labeled Compounds Calcineurin	Inflammation/Immunology
Cyclosporin A acetate-d₄ (Cyclosporine A acetate-d₄; Ciclosporin A acetate-d₄) is a deuterium labeled Cyclosporin A (HY-B0579) . Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM . Cyclosporin A also inhibits CD11a/CD18 adhesion .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-32349S

Ercalcidiol-d3 25-Hydroxy Vitamin D2-d<sub>3sub>	Endogenous Metabolite	Metabolic Disease
Ercalcidiol-d₃ is the deuterium labeled Ercalcidiol. Ercalcidiol is a metabolite of Vitamins D2. Ercalcidiol can be used as an indicator of vitamins D status .

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-32351S

Calcifediol-d3 25-hydroxy Vitamin D3-d<sub>3sub>	VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol-d₃ is a deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR ligand .

HY-N0682S3

Pyridoxine-13C4 hydrochloride Pyridoxol-¹³C<sub>4sub> hydrochloride; Vitamin B6-¹³C<sub>4sub> hydrochloride	Isotope-Labeled Compounds Endogenous Metabolite Keap1-Nrf2	Neurological Disease
Pyridoxine- ¹³C₄ (hydrochloride) is the ¹³C-labeled Pyridoxine (hydrochloride). Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

HY-16637S

Folic acid-d2 Vitamin B9-d<sub>2sub>; Vitamin M-d<sub>2sub>	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
Folic acid-d₂ (Vitamin B9-d₂) is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-112499S

Menaquinone-7-d7 Vitamin K2-7-d<sub>7sub>; Vitamin K2(35)-d<sub>7sub>; Vitamin MK-7-d<sub>7sub>	Isotope-Labeled Compounds	Cardiovascular Disease
Menaquinone-7-d₇ is the deuterium labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-15398S3

Vitamin D3-d3 Cholecalciferol-d<sub>3sub>; Colecalciferol-d<sub>3sub>	Bacterial Endogenous Metabolite VD/VDR	Metabolic Disease Cancer
Vitamin D3-d₃ is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.

HY-W016481S

4-Methoxybenzyl acetate-d3

Anisyl acetate-d<sub>3sub>
Isotope-Labeled Compounds Others

4-Methoxybenzyl acetate-d₃ is deuterated labeled cis-3-Hexenyl Acetate.

4-Methoxybenzyl acetate-d3 Anisyl acetate-d<sub>3sub>	Isotope-Labeled Compounds	Others
4-Methoxybenzyl acetate-d₃ is deuterated labeled cis-3-Hexenyl Acetate.

HY-B1008S

4-Aminobenzoic acid-d4 PABA-d<sub>4sub>; Vitamin Bx-d<sub>4sub>; Vitamin H1-d<sub>4sub>; p-Aminobenzoic acid-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
4-Aminobenzoic acid-d₄ is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.

HY-76542S

Vitamin D2-d6 Ergocalciferol-d<sub>6sub>; Calciferol-d<sub>6sub>; Ercalciol-d<sub>6sub>	VD/VDR Endogenous Metabolite	Metabolic Disease
Vitamin D2-d₆ is the deuterium labeled Vitamin D2. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D[1][2].

HY-75958S1

Vitamin D4-d5 22-Dihydroergocalciferol-d<sub>5sub>	VD/VDR	Metabolic Disease
Vitamin D4-d₅ is the deuterium labeled Vitamin D4. Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi. The precursor of Vitamin D4 is 22,23-dihydroergosterol[1].

HY-16637S3

Folic acid-13C5 Vitamin B9-¹³C<sub>5sub>; Vitamin M-¹³C<sub>5sub>	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
Folic acid- ¹³C₅ is the ¹³C-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-16760S

9-cis-Retinol acetate-d5 9-cis-Vitamin A acetate-d<sub>5sub>; Zuretinol acetate-d<sub>5sub>	Isotope-Labeled Compounds
9-cis-Retinol acetate-d₅ is the deuterium labeled 9-cis-Retinol acetate. 9-cis-Retinol acetate is a retinal derivative[1][2].

HY-B1342S1

Retinol-d6 Vitamin A1-d<sub>6sub>; all-trans-Retinol-d<sub>6sub>	Endogenous Metabolite	Metabolic Disease
Retinol-d₆ is the deuterium labeled Vitamin A. Retinol is an endogenous metabolite.

HY-75054S

Abiraterone acetate-d4 CB7630-d<sub>4sub>	Isotope-Labeled Compounds Cytochrome P450	Cancer
Abiraterone acetate-d₄ is the deuterium labeled Abiraterone acetate. Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. Abiraterone acetate is a proagent form of Abiraterone (CB7598).

HY-112499S1

Menaquinone-7-13C6 Vitamin K2-7-¹³C<sub>6sub>; Vitamin K2(35)-¹³C<sub>6sub>; Vitamin MK-7-¹³C<sub>6sub>	Isotope-Labeled Compounds	Cardiovascular Disease
Menaquinone-7- ¹³C₆ is the ¹³C-labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-B0150S

Nicotinamide-d4 Niacinamide-d<sub>4sub>; Nicotinic acid amide-d<sub>4sub>	Sirtuin Endogenous Metabolite	Neurological Disease Cancer
Nicotinamide-d₄ is the deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.

HY-B0511S1

rel-Biotin-d4 rel-Vitamin B7-d<sub>4sub>; rel-Vitamin H-d<sub>4sub>; rel-D-Biotin-d<sub>4sub>	Endogenous Metabolite	Metabolic Disease
rel-Biotin-d₄ is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-B2209

Hydroxocobalamin 1 Publications Verification Vitamin B12a	Endogenous Metabolite	Metabolic Disease
Hydroxocobalamin (Vitamin B12a) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-N0684S3

Vitamin K1-13C6 Phylloquinone-¹³C<sub>6sub>; Phytomenadione-¹³C<sub>6sub>	Endogenous Metabolite	Cardiovascular Disease
Vitamin K1- ¹³C₆ is the ¹³C-labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-B1278AS

DL-α-Tocopherol acetate-13C4,d6 Vitamin E acetate-¹³C<sub>4sub>,d<sub>6sub>	Endogenous Metabolite	Inflammation/Immunology
DL-α-Tocopherol acetate- ¹³C₄,d₆ is the deuterium and ¹³C labeled DL-α-Tocopherol acetate[1]. DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition[2][3].

HY-15398S4

Vitamin D3-13C5 Cholecalciferol-¹³C<sub>5sub>; Colecalciferol-¹³C<sub>5sub>	Bacterial VD/VDR	Infection Endocrinology
Vitamin D3- ¹³C₅ is the deuterium labeled Vitamin D3 (HY-15398). Vitamin D3 (Cholecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells[1][2].

HY-N7148S

*α-Vitamin* E-d6** (+)-α-Tocopherol-d<sub>6sub>; D-α-Tocopherol-d<sub>6sub>	COX Endogenous Metabolite Isotope-Labeled Compounds	Others
α-Vitamin E-d₆ is the deuterium labeled α-Vitamin E[1].

HY-N0682S2

Pyridoxine-d5 hydrochloride Pyridoxol-d<sub>5sub> hydrochloride; Vitamin B6-d<sub>5sub> hydrochloride	Keap1-Nrf2 Endogenous Metabolite
Pyridoxine-d₅ (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride[1]. Pyridoxine hydrochloride (Pyridoxol;Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol;Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway[2].

HY-N0680S2

Thiamine-d4 hydrochloride Thiamine chloride-d<sub>4sub> hydrochloride; Vitamin B1-d<sub>4sub> hydrochloride	Endogenous Metabolite Apoptosis HBV	Neurological Disease
Thiamine-d₄ (hydrochloride) is deuterium labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-32351AS

Calcifediol-d6 monohydrate 25-hydroxy Vitamin D3-d<sub>6sub> monohydrate	Isotope-Labeled Compounds VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol-d₆ (monohydrate) is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), a major circulating metabolite of vitamin D3, is a potent VDR ligand .

HY-N0682S

Pyridoxine-d3 hydrochloride Pyridoxol-d<sub>3sub> (hydrochloride); Vitamin B6-d<sub>3sub> (hydrochloride)	Endogenous Metabolite Keap1-Nrf2	Neurological Disease
Pyridoxine-d₃ (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

HY-B2209C

Hydroxocobalamin hydrochloride Vitamin B12a hydrochloride	Endogenous Metabolite	Metabolic Disease
Hydroxocobalamin hydrochloride is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the research of vitamin B12 deficiency including pernicious anemia .

HY-B0332S

Menadione-d3 Vitamin K3-d<sub>3sub>	Endogenous Metabolite	Others
Menadione-d₃ is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo.

HY-B0143S3

Niacin-13C6 Nicotinic acid-¹³C<sub>6sub>; Vitamin B3-¹³C<sub>6sub>	Autophagy Endogenous Metabolite	Metabolic Disease
Niacin- ¹³C₆ is the ¹³C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

HY-B1342S3

Retinol-13C3 Vitamin A1-¹³C<sub>3sub>; all-trans-Retinol-¹³C<sub>3sub>	Isotope-Labeled Compounds	Others
Retinol- ¹³C₃ (Vitamin A1- ¹³C₃; all-trans-Retinol- ¹³C₃) is a ¹³C-labeled Vitamin A/Retinol (HY-B1342). Retinol is an endogenous metabolite.

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-N0683S

*α-Vitamin* E-13C6** (+)-α-Tocopherol-¹³C<sub>6sub>; D-α-Tocopherol-¹³C<sub>6sub>	Bacterial Influenza Virus Reactive Oxygen Species Ferroptosis Endogenous Metabolite	Infection Cancer
α-Vitamin E- ¹³C₆ is the ¹³C-labeled α-Vitamin E. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[1][2].

HY-N0683S1

*α-Vitamin* E-13C3** (+)-α-Tocopherol-¹³C<sub>3sub>; D-α-Tocopherol-¹³C<sub>3sub>	Bacterial Influenza Virus Reactive Oxygen Species Ferroptosis Endogenous Metabolite	Infection Cancer
α-Vitamin E- ¹³C₃ is the ¹³C-labeled α-Vitamin E. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[1][2].

HY-B2156S

Menaquinone-4-d7 Vitamin K2(MK-4)-d<sub>7sub>; Menaquinone K4-d<sub>7sub>	Endogenous Metabolite	Cancer
Menaquinone-4-d₇ (Vitamin K2(MK-4)-d7) is the deuterium labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-16637S2

(Rac)-Folic acid-13C5,15N (Rac)-Vitamin B9-¹³C<sub>5sub>,¹⁵N; (Rac)-Vitamin M-¹³C<sub>5sub>,¹⁵N	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite	Cancer
(Rac)-Folic acid- ¹³C₅, ¹⁵N is the ¹³C-labeled and ¹⁵N-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-B1508

Vitamin K4 Acetomenaphthone	Endogenous Metabolite Apoptosis	Cardiovascular Disease Cancer
Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system. Vitamin K4 arrests the cells in S phase and induces apoptosis. Vitamin K4 can be used for the research of cancer, such as prostate cancer and osteosarcoma .

HY-13332

Calcifediol-d6 25-hydroxy Vitamin D3-d<sub>6sub>	VD/VDR	Metabolic Disease
Calcifediol-d₆ is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].

HY-15331

VD3-d6

Vitamin D3-26,26,26,27,27,27-d<sub>6sub>
VD/VDR Metabolic Disease

VD3-d₆ is the deuterium labeled Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.

VD3-d6 Vitamin D3-26,26,26,27,27,27-d<sub>6sub>	VD/VDR	Metabolic Disease
VD3-d₆ is the deuterium labeled Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.

HY-B0143

Niacin 5+ Cited Publications Nicotinic acid; Vitamin B3	Autophagy Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Cancer
Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases .

HY-32351AS1

Calcifediol-13C5 monohydrate 25-Hydroxy Vitamin D3-¹³C<sub>5sub> monohydrate	Isotope-Labeled Compounds VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol- ¹³C₅ (monohydrate) is the ¹³C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), a major circulating metabolite of vitamin D3, is a potent VDR ligand .

HY-N0682S1

Pyridoxine-d2 hydrochloride Pyridoxol-d<sub>2sub> (hydrochloride); Vitamin B6-d<sub>2sub> (hydrochloride)	Endogenous Metabolite Keap1-Nrf2	Neurological Disease
Pyridoxine-d₂ (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

HY-B0511A

Biotin sodium Vitamin B7 sodium; Vitamin H sodium; D-Biotin sodium	Endogenous Metabolite	Metabolic Disease
Biotin (Vitamin B7) sodium is a water-soluble B vitamin and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin sodium is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

HY-B0579S

Cyclosporin A-d4 Cyclosporine A-d<sub>4sub>; Ciclosporin A-d<sub>4sub>; CsA-d<sub>4sub>	Antibiotic Complement System Phosphatase	Inflammation/Immunology Cancer
Cyclosporin A-d₄ is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 ad

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B2209

Hydroxocobalamin 1 Publications Verification Vitamin B12a	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxocobalamin (Vitamin B12a) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-B1508

Vitamin K4 Acetomenaphthone	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Apoptosis
Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system. Vitamin K4 arrests the cells in S phase and induces apoptosis. Vitamin K4 can be used for the research of cancer, such as prostate cancer and osteosarcoma .

HY-B0143

Niacin 5+ Cited Publications Nicotinic acid; Vitamin B3	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields	Autophagy Endogenous Metabolite
Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases .

HY-B2209C

Hydroxocobalamin hydrochloride Vitamin B12a hydrochloride	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxocobalamin hydrochloride is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the research of vitamin B12 deficiency including pernicious anemia .

HY-B0511A

Biotin sodium Vitamin B7 sodium; Vitamin H sodium; D-Biotin sodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Biotin (Vitamin B7) sodium is a water-soluble B vitamin and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin sodium is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

HY-B0332

Menadione 10+ Cited Publications Vitamin K3	Quinones Structural Classification Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Naphthalene Quinones Disease Research Fields	Endogenous Metabolite
Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer .

HY-W011474

Geranylgeraniol	Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[4].

HY-B0143A

Niacin hydrochloride Nicotinic acid hydrochloride; Vitamin B3 hydrochloride	Structural Classification Alkaloids Classification of Application Fields Ketones, Aldehydes, Acids Source classification Pyridine Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Apoptosis
Niacin (Vitamin B3; Nicotinic acid) hydrochloride is an orally active B3 vitamin that is an essential nutrient for humans. Niacin hydrochloride plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin hydrochloride is also used in the study of cardiovascular diseases .

HY-B0430B

(±)-Pantothenic acid (±)-Pantothenate; (±)-Vitamin B5	Other disease Disease markers Endogenous metabolite	Others
(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is an essential vitamin required for the biosynthesis of coenzyme A (CoA) in mammalian cells. Pantothenic acid has protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD-1 mice .

HY-B0511

Biotin 5+ Cited Publications Vitamin B7; Vitamin H; D-Biotin	Structural Classification other families Microorganisms Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Metabolic Disease Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

HY-125833

Alpha-Naphthoflavone 5 Publications Verification	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[4].

HY-B0757A

(±)-α-Tocopherol nicotinate Vitamin E Nicotinate	Cardiovascular Disease Structural Classification Alkaloids Classification of Application Fields Source classification Pyridine Alkaloids Endogenous metabolite Disease Research Fields	Reactive Oxygen Species Endogenous Metabolite
(±)-α-Tocopherol nicotinate, vitamin E - nicotinate, is an orally active fat-soluble antioxidant that prevents lipid peroxidation in cell membranes. (±)-α-Tocopherol nicotinate is hydrolysed in the blood to α -tocopherol and niacin and may be used in studies of related vascular diseases .

HY-B2209B

Hydroxocobalamin acetate 1 Publications Verification Vitamin B12a acetate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxocobalamin acetate is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the research of vitamin B12 deficiency including pernicious anemia .

HY-N8357

Vitamin D3 octanoate	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Vitamin D3 octanoate is an octanoate ester of vitamin D3 . Vitamin D3 (Cholecalciferol; HY-15398) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells .

HY-B0315A

*Biotin-Vitamin* B12**	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Biotin-Vitamin B12 is the biotinylated Vitamin B12. Vitamin B12 is a vitamin that plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood .

HY-B2209A

Hydroxocobalamin monohydrochloride 1 Publications Verification Vitamin B12a monohydrochloride	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxocobalamin monohydrochloride (Vitamin B12a monohydrochloride) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-N8356

*13-cis-Vitamin* A palmitate** 13-cis-Retinyl palmitate	Zea mays L. Classification of Application Fields Terpenoids Gramineae Source classification Other Diseases Diterpenoids Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
13-cis-Vitamin A palmitate (13-cis-Retinyl palmitate) is a 13-cis isomer formed by vitamin A palmitate in corn flakes. 13-cis-Vitamin A palmitate has a biological activity of 75% of all-trans-vitamin A palmitate, the most biologically ac-tive form of vitamin A .

HY-N8356A

*9-cis-Vitamin* A palmitate** 9-cis-Retinyl palmitate	Classification of Application Fields Terpenoids Source classification Other Diseases Diterpenoids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
9-cis-Vitamin A palmitate (9-cis-Retinyl palmitate) is a 9-cis isomer formed by vitamin A palmitate in corn flakes. 9-cis-Vitamin A palmitate has a biological activity of 26% of all-trans-vitamin A palmitate, the most biologically ac-tive form of vitamin A .

HY-B2172

Vitamin K	Cardiovascular Disease Natural Products other families Microorganisms Classification of Application Fields Animals Source classification Plants Disease Research Fields	Endogenous Metabolite
Vitamin K, the blood-clotting vitamin, is important for the function of numerous proteins within the body, such as the coagulation factors, osteocalcin and matrix-Gla protein.

HY-B0315

Vitamin B12 2 Publications Verification Cyanocobalamin	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood .

HY-15398

Vitamin D3 5+ Cited Publications Cholecalciferol; Colecalciferol	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Anti-aging Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Cancer	VD/VDR Endogenous Metabolite Bacterial
Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.

HY-N2551

Vitamin U chloride S-Methylmethionine sulfonium chloride	Plants Compositae	Others
Vitamin U (S-Methylmethionine sulfonium) chloride is an orally active anti-ulcer agent with antioxidant activity. Vitamin U inhibits adipocyte differentiation. Vitamin U promotes skin wound healing.Vitamin U can be used in the research of gastrointestinal ulceration ^[4] .

HY-N0684

Vitamin K1 2 Publications Verification Phylloquinone; Phytomenadione	Cardiovascular Disease Quinones Human Gut Microbiota Metabolites other families Microorganisms Classification of Application Fields Source classification Plants Endogenous metabolite Naphthalene Quinones Disease Research Fields	Endogenous Metabolite
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-16637

Folic acid 5+ Cited Publications Vitamin B9; Vitamin M	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Endocrine diseases Plants Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms other families Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Cancer	DNA/RNA Synthesis Endogenous Metabolite
Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency ^[4].

HY-16637A

Folic acid sodium Vitamin B9 sodium; Vitamin M sodium	Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Endogenous Metabolite
Folic acid (Vitamin B9) sodium is a orally active essential nutrient from the B complex group of vitamins. Folic acid sodium shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid sodium can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency ^[4].

HY-109569

Vitamin K2	Other Terpenoids Classification of Application Fields Terpenoids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Vitamin K2 is an endogenous metabolite.

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-15127

Isotretinoin 4 Publications Verification 13-cis-Retinoic acid	Structural Classification Classification of Application Fields Terpenoids Source classification Diterpenoids Endogenous metabolite Disease Research Fields Cancer	RAR/RXR Endogenous Metabolite Autophagy
Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity .

HY-32349

Ercalcidiol 1 Publications Verification 25-Hydroxy Vitamin D2	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	VD/VDR Endogenous Metabolite
Ercalcidiol is a metabolite of vitamin D₂, is regarded as an indicator of vitamin D nutritional status.

HY-B2209BR

Hydroxocobalamin acetate (Standard) Vitamin B12a acetate (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Hydroxocobalamin (acetate) (Standard) is the analytical standard of Hydroxocobalamin (acetate). This product is intended for research and analytical applications. Hydroxocobalamin acetate is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the research of vitamin B12 deficiency including pernicious anemia .

HY-A0100

Thiamine monochloride Vitamin B1	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite Bacterial
Thiamine monochloride (Vitamin B1) is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal actives.

HY-N0684A

*cis-Vitamin* K1** cis-Phylloquinone; cis-Phytomenadione	Cardiovascular Disease Quinones Structural Classification Classification of Application Fields Source classification Endogenous metabolite Naphthalene Quinones Disease Research Fields	Endogenous Metabolite
Cis-Vitamin K1 is an endogenous metabolite of Vitamin K .

HY-76542

Vitamin D2 1 Publications Verification Ergocalciferol; Calciferol; Ercalciol	Human Gut Microbiota Metabolites other families Microorganisms Classification of Application Fields Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields Steroids	VD/VDR Endogenous Metabolite
Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D .

HY-145806

13-cis-Retinyl acetate 13-cis-Retinol acetate; 13-cis-Vitamin A acetate	Structural Classification Classification of Application Fields Terpenoids Source classification Diterpenoids Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite
13-cis-Retinyl acetate (13-cis-Retinol acetate; 13-cis-Vitamin A acetate) is a 13-cis isomer formed by Retinyl acetate. 13-cis-Retinyl acetate is an active metabolite of vitamin A .

HY-32351

Calcifediol 5+ Cited Publications 25-hydroxy Vitamin D3	Structural Classification Natural Products Microorganisms Classification of Application Fields Other disease Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields	VD/VDR Endogenous Metabolite
Calcifediol (25-hydroxy Vitamin D3), a major circulating metabolite of vitamin D3, is a potent VDR ligand .

HY-32351A

Calcifediol monohydrate 5+ Cited Publications 25-hydroxy Vitamin D3 monohydrate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	VD/VDR Endogenous Metabolite
Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), a major circulating metabolite of vitamin D3, is a potent VDR ligand .

HY-N0683A

*rel-α-Vitamin* E** rel-D-α-Tocopherol	Natural Products Monophenols other families Classification of Application Fields Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Others
rel-α-Vitamin E (rel-D-α-Tocopherol) is a vitamin with antioxidant properties and also a mixture .

HY-N0682

Pyridoxine hydrochloride 5 Publications Verification Pyridoxol hydrochloride; Vitamin B6 hydrochloride	Alkaloids Source classification Pyridine Alkaloids Endogenous metabolite	Endogenous Metabolite Keap1-Nrf2
Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

HY-32350

Ercalcitriol 2 Publications Verification 1α,25-Dihydroxy Vitamin D2	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	VD/VDR Drug Metabolite Endogenous Metabolite
Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2.

HY-B1278A

DL-α-Tocopherol acetate 2 Publications Verification Vitamin E acetate	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition.

HY-N0683

*α-Vitamin* E** 10+ Cited Publications (+)-α-Tocopherol; D-α-Tocopherol	Infection Classification of Application Fields Moisture Cosmetic Research Disease Research Fields Cancer Food Research	Bacterial Influenza Virus Reactive Oxygen Species Ferroptosis Endogenous Metabolite
α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant .

HY-B2223

Thiamine nitrate Vitamin B1 nitrate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Bacterial
Thiamine nitrate is an essential vitamin which can enhance normal neuronal actives.

HY-N0681

D-Pantothenic acid hemicalcium salt 3 Publications Verification Calcium pantothenate; Calcium D-pantothenate; Vitamin B5 calcium salt	Natural Products other families Classification of Application Fields Source classification Other Diseases Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite Apoptosis
D-Pantothenic acid hemicalcium salt (Vitamin B5 calcium salt), a vitamin, can reduce the patulin content of the apple juice.

HY-76915

24, 25-Dihydroxy VD3	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	VD/VDR Endogenous Metabolite
24, 25-Dihydroxy VD3 is a compound closely related to 1,25-dihydroxyvitamin D3 and is the active form of vitamin D3 .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-14649

Retinoic acid 45+ Cited Publications Vitamin A acid; all-trans-Retinoic acid; ATRA	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Whitening Agent Cosmetic Research Endogenous metabolite Disease Research Fields Cancer	Organoid RAR/RXR PPAR Endogenous Metabolite Autophagy
Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with K_d of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-B2156

Menaquinone-4 Vitamin K2(MK-4); Menaquinone K4	Quinones Structural Classification Microorganisms other families Classification of Application Fields Source classification Plants Endogenous metabolite Naphthalene Quinones Disease Research Fields Cancer	Endogenous Metabolite
Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Disease Research Fields Selaginella tamariscina (P. Beauv.) Spring Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[4].

HY-113462

α-Carotene	Structural Classification Classification of Application Fields Source classification Plants Food Research Other Terpenoids Microorganisms Terpenoids Pigments Decachaeta ovatifolia (DC.) R.M.King & H.Rob. Umbelliferae Disease Research Fields Cancer	Others
α-Carotene, a precursor of vitamin A, is used as an anti-metastatic agent or as an adjuvant for anti-cancer agents. α-Carotene is isolated from yellow-orange and dark-green vegetables .

Cat. No.	Product Name	Chemical Structure

HY-B0143S2

Niacin-d4

Niacin-d₄ is the deuterium labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.

HY-N0679S4

Retinyl acetate-d4
Retinyl acetate-d₄ is the deuterium labeled Retinyl acetate[1]. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities[2].

HY-16637S1

Folic acid-d4
Folic acid-d₄ is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-N0684S1

Vitamin K1-d4

Vitamin K1-d₄ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1].

HY-B0579S2

Cyclosporin A acetate-d4
Cyclosporin A acetate-d₄ (Cyclosporine A acetate-d₄; Ciclosporin A acetate-d₄) is a deuterium labeled Cyclosporin A (HY-B0579) . Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM . Cyclosporin A also inhibits CD11a/CD18 adhesion .

HY-32349S

Ercalcidiol-d3

Ercalcidiol-d₃ is the deuterium labeled Ercalcidiol. Ercalcidiol is a metabolite of Vitamins D2. Ercalcidiol can be used as an indicator of vitamins D status .
HY-32351S

Calcifediol-d3

Calcifediol-d₃ is a deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR ligand .

HY-N0682S3

Pyridoxine-13C4 hydrochloride
Pyridoxine- ¹³C₄ (hydrochloride) is the ¹³C-labeled Pyridoxine (hydrochloride). Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

HY-16637S

Folic acid-d2
Folic acid-d₂ (Vitamin B9-d₂) is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-112499S

Menaquinone-7-d7

Menaquinone-7-d₇ is the deuterium labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-15398S3

Vitamin D3-d3
Vitamin D3-d₃ is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.

HY-W016481S

4-Methoxybenzyl acetate-d3

4-Methoxybenzyl acetate-d₃ is deuterated labeled cis-3-Hexenyl Acetate.

HY-B1008S

4-Aminobenzoic acid-d4
4-Aminobenzoic acid-d₄ is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.

HY-76542S

Vitamin D2-d6
Vitamin D2-d₆ is the deuterium labeled Vitamin D2. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D[1][2].

HY-75958S1

Vitamin D4-d5
Vitamin D4-d₅ is the deuterium labeled Vitamin D4. Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi. The precursor of Vitamin D4 is 22,23-dihydroergosterol[1].

HY-16637S3

Folic acid-13C5
Folic acid- ¹³C₅ is the ¹³C-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-16760S

9-cis-Retinol acetate-d5

9-cis-Retinol acetate-d₅ is the deuterium labeled 9-cis-Retinol acetate. 9-cis-Retinol acetate is a retinal derivative[1][2].
HY-B1342S1

Retinol-d6

Retinol-d₆ is the deuterium labeled Vitamin A. Retinol is an endogenous metabolite.

HY-75054S

Abiraterone acetate-d4
Abiraterone acetate-d₄ is the deuterium labeled Abiraterone acetate. Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. Abiraterone acetate is a proagent form of Abiraterone (CB7598).

HY-112499S1

Menaquinone-7-13C6

Menaquinone-7- ¹³C₆ is the ¹³C-labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-B0150S

Nicotinamide-d4
Nicotinamide-d₄ is the deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.

HY-B0511S1

rel-Biotin-d4

rel-Biotin-d₄ is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
HY-N0684S3

Vitamin K1-13C6

Vitamin K1- ¹³C₆ is the ¹³C-labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-B1278AS

DL-α-Tocopherol acetate-13C4,d6
DL-α-Tocopherol acetate- ¹³C₄,d₆ is the deuterium and ¹³C labeled DL-α-Tocopherol acetate[1]. DL-α-Tocopherol acetate is a vitamin E derivative which is often included in the formulations of enteral nutrition[2][3].

HY-15398S4

Vitamin D3-13C5
Vitamin D3- ¹³C₅ is the deuterium labeled Vitamin D3 (HY-15398). Vitamin D3 (Cholecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells[1][2].

HY-N7148S

α-Vitamin E-d6

α-Vitamin E-d₆ is the deuterium labeled α-Vitamin E[1].

HY-N0682S2

Pyridoxine-d5 hydrochloride
Pyridoxine-d₅ (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride[1]. Pyridoxine hydrochloride (Pyridoxol;Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol;Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway[2].

HY-N0680S2

Thiamine-d4 hydrochloride
Thiamine-d₄ (hydrochloride) is deuterium labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-32351AS

Calcifediol-d6 monohydrate
Calcifediol-d₆ (monohydrate) is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), a major circulating metabolite of vitamin D3, is a potent VDR ligand .

HY-N0682S

Pyridoxine-d3 hydrochloride
Pyridoxine-d₃ (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

HY-B0332S

Menadione-d3

Menadione-d₃ is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo.
HY-B0143S3

Niacin-13C6

Niacin- ¹³C₆ is the ¹³C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.
HY-B1342S3

Retinol-13C3

Retinol- ¹³C₃ (Vitamin A1- ¹³C₃; all-trans-Retinol- ¹³C₃) is a ¹³C-labeled Vitamin A/Retinol (HY-B1342). Retinol is an endogenous metabolite.

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-N0683S

α-Vitamin E-13C6

α-Vitamin E- ¹³C₆ is the ¹³C-labeled α-Vitamin E. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[1][2].
HY-N0683S1

α-Vitamin E-13C3

α-Vitamin E- ¹³C₃ is the ¹³C-labeled α-Vitamin E. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[1][2].

HY-B2156S

Menaquinone-4-d7
Menaquinone-4-d₇ (Vitamin K2(MK-4)-d7) is the deuterium labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-16637S2

(Rac)-Folic acid-13C5,15N
(Rac)-Folic acid- ¹³C₅, ¹⁵N is the ¹³C-labeled and ¹⁵N-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-13332

Calcifediol-d6

Calcifediol-d₆ is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].
HY-15331

VD3-d6

VD3-d₆ is the deuterium labeled Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.

HY-32351AS1

Calcifediol-13C5 monohydrate
Calcifediol- ¹³C₅ (monohydrate) is the ¹³C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), a major circulating metabolite of vitamin D3, is a potent VDR ligand .

HY-N0682S1

Pyridoxine-d2 hydrochloride
Pyridoxine-d₂ (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

HY-B0579S

Cyclosporin A-d4
Cyclosporin A-d₄ is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 ad

HY-B1203AS

Fludrocortisone acetate-d5

Fludrocortisone acetate-d₅ is deuterium labeled Fludrocortisone acetate.
HY-41680S

4-Aminobenzonitrile-d4

4-Aminobenzonitrile-d₄ is the deuterium labeled 4-Aminobenzonitrile[1].

HY-66005S

Acetaminophen-d4
Acetaminophen-d₄ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

HY-14649S4

Retinoic acid-d5

Retinoic acid-d₅ is the the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with K_d of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha ^[4] .

HY-Y1042S

4-Cyanophenol-d4

4-Cyanophenol-d₄ is the deuterium labeled 4-Cyanophenol[1].

HY-14649S3

Retinoic acid-d6

Retinoic acid-d₆ is the deuterium labeled Retinoic acid[1]. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[2][3][4][5][6][7].

HY-W102356S2

Phenethyl acetate-d5

Phenethyl acetate-d₅ is deuterated labeled Phenethyl acetate.

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Species:	Human (1521) Porcine (2) Rhesus Macaque (50) Rat (121) Bovine (2) Xenopus laevis (3) Cynomolgus (92) E.coli (11) Rabbit (9) Pig (9) Canine (25) Virus (617) Marmoset (3) Mouse (503) Cat (1) Dog (3) Staphylococcus aureus (8)
Tag:	SUMO (49) T7 (1) GST (80) Flag (61) GFP (5) His (2249) Strep (19) Tag Free (311) Avi (248) Myc (29) HSA (1) MBP (32) Trx (4) Fc (378) B2M (5)
Source:	HEK293 (1913) E. coli Cell-free (47) CHO (3) CHO (22) Sf9 insect cells (5) Sf9 insect cells (350) P. pastoris (59) E. coli (584)


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